Comparison

The best EHR clinical trial matching software in 2026

EHR clinical trial matching software reads a site's own patient records against a study's eligibility criteria and returns the patients who may qualify. We compared five tools on what they read in the chart, the evidence behind each match, what happens after the match, who they serve and how they charge. Bond Health ranks first because it is the only one whose public materials describe software that also contacts, pre-screens and books every matched patient.⁠[1],[2]

By Rishabh Goel, CEO · Reviewed by Steven Tan, Security LeadLast updated Nov 8, 202629 sources
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What is the best EHR clinical trial matching software?

  1. 1[Bond Health](/what-is-bond-health): best overall, and best for sites that want matches turned into booked visits. It screens the EHR, including clinical notes, then its voice and text agents contact, pre-screen and book every match, in any therapeutic area.⁠[1],[2]
  2. 2Tempus (Deep 6 AI, TIME and Next Trials): for oncology practices in a sponsor-funded trial network. Tempus acquired Deep 6 AI in 2025 and sells trial matching through its TIME oncology network and Next Trials.⁠[3],[7],[6]
  3. 3Triomics: built for cancer centers on Epic, OncoEMR or iKnowMed. Its PRISM product screens the upcoming clinic schedule against every active trial and sends matches to staff before clinic.⁠[14],[15]
  4. 4Paradigm Health: for providers that want a research partner with its own staff. It combines its platform with recruitment coordinators and eligibility specialists who work alongside site teams.⁠[16],[19]
  5. 5TriNetX: for sponsors and CROs choosing sites, not for contacting patients. Sponsors query a federated network of member organizations' EHR data for feasibility and site selection, and each organization re-identifies its own eligible patients.⁠[25],[26]

Mendel, once a common name on lists like this, is no longer sold on its own: its investor lists it as merged into Ensemble Health Partners.⁠[23] See Deep 6 AI vs Mendel.

Why is Bond the best EHR clinical trial matching software?

10,000+⁠[1]

charts screened per hour

90%+⁠[1]

matching accuracy in eligibility screening

48 hours⁠[1]

to full EHR integration, with no integration fee

  • The whole chart, not just codes. Identify reads structured fields and clinical notes, prescriptions and lab results, plus imaging data and pathology, radiology and molecular reports.⁠[1],[2]
  • Evidence behind every criterion. Each ranked match comes with the evidence behind each criterion decision and traceability to the chart, and Bond's site cites 50%+ less chart review.⁠[1]
  • Matches become visits. Bond's agents start from what Identify found in the chart, skip questions the chart already answers, and can pre-screen and book a visit in one conversation, in the patient's language.⁠[2]
  • Every ad lead contacted immediately, and followed up until they book. Bond creates and runs Meta and Google ad campaigns for each study. Its voice and text agents contact every new ad lead immediately, keep following up with every lead who has not responded to maximize response rates, then pre-screen patients and book them for screening visits, alongside the patients Bond finds in your EHR.⁠[2]
  • Any therapeutic area, any EHR. Screening is configured from each protocol's own criteria. Bond connects to Epic, Oracle Health (Cerner), MEDITECH, athenahealth, eClinicalWorks, NextGen, Veradigm and OncoEMR, and works with CRIO, Advarra OnCore, Advarra Clinical Conductor, RealTime and Veeva SiteVault.⁠[1],[2]
  • A price that follows enrollment. A volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee. See pricing.⁠[2]

How did we evaluate EHR trial matching software?

We read each vendor's own website, press releases, filings and published customer work in October and November 2026, and scored the tools on what a research site needs to get from a protocol to an enrolled patient:

  • What it reads. Structured codes alone miss criteria that live in notes and reports, such as disease stage, prior lines of therapy or a symptom history.
  • The evidence behind each match. Coordinators trust, and can audit, a match that shows the chart text behind each criterion.
  • What happens after the match. Someone has to call the patient, pre-screen them and book the visit. We checked whether the vendor's software does it, whether its own staff do, or whether it is left to the site.
  • Who it serves. Some tools are built for one therapeutic area, one EHR or one kind of customer.
  • Connections and pricing. Which EHRs and CTMS systems it connects to, and whether pricing is public.

"Not publicly documented" in the table means we found no public description in the materials we reviewed, not that the capability is absent.

How do the tools compare, side by side?

EHR clinical trial matching software, from public materials reviewed in October and November 2026
ToolBest forWhat it readsAfter the matchPricing
Bond HealthResearch sites, site networks, physician groups, FQHCs, CROs and sponsors, in any therapeutic area.⁠[1]Structured fields and clinical notes, prescriptions and lab results, plus imaging data and pathology, radiology and molecular reports, with evidence behind each criterion.⁠[1],[2]Bond's voice and SMS agents contact every matched patient, pre-screen them and book the visit on the site's calendar. Bond also runs Meta and Google ads and contacts every ad lead immediately.⁠[1],[2]A volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee (pricing).⁠[2]
Tempus (Deep 6 AI, TIME, Next Trials)Health systems running trials enterprise-wide (Deep 6 AI, 2024), and oncology practices (TIME and Next Trials, 2026).⁠[8],[7],[6]Structured and unstructured EMR data, including physician notes and lab, radiology, pathology and genomics reports (2023, 2025); clinical, imaging and molecular data for Next Trials (2026).⁠[10],[4],[6]Deep 6 AI sent matches to site staff to validate and track (2023). For TIME, a Tempus clinical team pre-screens matched patients and presents them to each site (2026). Automated calls or texts and visit booking: not publicly documented.⁠[9],[5]No public price list found. Tempus names the trial sponsor as the TIME customer (2026).⁠[3]
TriomicsCancer centers, with native integrations for Epic, OncoEMR and iKnowMed (2026).⁠[13],[15]Every note, report and fax in the record, from HL7, FHIR, CCDA and XML data to PDFs and images, with cited answers (2026).⁠[13],[15]Matches arrive as an EHR in-basket message, a worklist entry or an email to staff before clinic (2026). Patient outreach: not publicly documented.⁠[14]No public price list found; the website offers a demo (2026).⁠[13]
Paradigm HealthCommunity providers and academic medical centers that want a research partner, and the sponsors whose trials it brings to them (2026).⁠[18],[17]Structured and unstructured clinical data against protocol criteria (2026), including clinical notes and pathology reports (2024).⁠[19],[20]Paradigm's recruitment coordinators and eligibility specialists help site teams with outreach, follow-up, pre-screening and consent (2026). Automated calls or texts: not publicly documented.⁠[19],[17]No public price list found. In 2023 its customers were trial sponsors, not health systems.⁠[22]
TriNetXSponsors and CROs judging protocol feasibility and choosing sites across a federated network of member healthcare organizations (2023, 2026).⁠[28],[25]Demographics, diagnoses, procedures, medications and lab results, as discrete data or from NLP of notes and reports, de-identified for network queries (2023, 2026).⁠[28],[25]Sends study opportunities to organizations and sites, and the organization re-identifies eligible patients itself (2026). Contacting patients: not publicly documented.⁠[27],[26]Sponsors and CROs fund the platform; member organizations incur no financial costs (2023). No public price list found.⁠[28]

Years show each source's date. See all recruitment software, one table for the wider category.

What does each tool do best?

1. Bond Health

Bond is the one tool here that covers the whole path from chart to booked visit. Identify ranks matches with chart evidence, Engage calls and texts each patient in their own language, and Book puts the pre-screened patient on the site's calendar, with consent support and retention after that. Bond serves any therapeutic area and any research site, from physician groups and FQHCs to site networks, CROs and sponsors.⁠[1],[2] Ideal for: sites that do not have coordinator hours to call every match, and sponsors who want one enrollment funnel across sites.

2. Tempus (Deep 6 AI, TIME and Next Trials)

Tempus acquired Deep 6 AI on March 11, 2025.⁠[3] Deep 6 AI applied NLP to physician notes and lab, radiology, pathology and genomics reports, and Ohio State described it highlighting the text behind each criterion.⁠[10],[11] Tempus now sells trial matching through TIME, its oncology trial network, where a Tempus clinical team pre-screens matched patients for each site, and Next Trials, which pre-screens for trials already open at a practice.⁠[5],[6] Ideal for: oncology practices that want to join a sponsor-funded trial network. See Bond vs Tempus (Deep 6 AI).

3. Triomics

Triomics is built for cancer care. Its PRISM product screens patients on tomorrow's schedule and the week ahead against every active trial, refreshes nightly, and sends matches into the EHR in-basket, a worklist or email before clinic. It integrates natively with Epic, OncoEMR and iKnowMed.⁠[14],[15] Ideal for: cancer centers whose coordinators want matches flagged before the patient's visit. See Deep 6 AI vs Triomics.

4. Paradigm Health

Paradigm Health sells a platform plus people: its software evaluates structured and unstructured data against protocol criteria, and its recruitment coordinators and eligibility specialists work alongside site teams.⁠[19] In December 2025 it announced it would acquire Flatiron Health's clinical research business and integrate its tools into Flatiron's OncoEMR.⁠[21] Ideal for: community providers that want an outside team to bring in and run sponsor trials. See Deep 6 AI vs Paradigm Health.

5. TriNetX

TriNetX is a different kind of tool: a network of healthcare organizations' EHR data that sponsors and CROs query for aggregate patient counts at each organization, to judge feasibility and choose sites. Through TriNetX LIVE™ Connect they invite organizations to studies, and each organization re-identifies its own eligible patients.⁠[28],[25],[26] At Weill Cornell Medicine it brought 402 sponsor trial requests over six years, and local investigators were interested in 14% of them.⁠[29] Ideal for: sponsors and CROs choosing sites. A site that accepts the study still has to find, contact and book the patients, which is where Bond fits. See Bond vs TriNetX.

How should a site choose EHR trial matching software?

Start with who will act on each match. If your coordinators already have hours to call every patient, a match list may be enough. If they do not, the software has to contact, pre-screen and book patients itself, or matches will sit in a worklist.

  1. 1

    Pick a study with a known answer

    Use a closed or mature study where coordinators know who enrolled, who screen-failed and why.

  2. 2

    Give every vendor the same protocol and records

    Ask each for the chart evidence behind every criterion decision, not only a score, and adjudicate borderline cases separately.

  3. 3

    Measure what happens after the match

    Track who contacts each matched patient, how fast, how many are reached and how many reach a screening visit.

  4. 4

    Compare cost per randomized patient

    Add platform, integration and staff time, then divide by randomized patients. See the cost per randomized patient calculator.

  5. 5

    Compare the paperwork

    BAA, audit logging, data-use terms and who does the IT work. Ask each vendor whether data from your connection is de-identified, retained or licensed to others. Bond signs BAAs; see security.⁠[1]

The vendor evaluation checklist turns these steps into questions, and using the EHR for recruitment explains what the chart can and cannot tell you about eligibility.

Bring one protocol. We will show how Bond handles its hardest criteria and the evidence behind each decision, and plan a head-to-head pilot on your records.

Book a demoRead about Identify

How was this comparison made?

Bond wrote this page in November 2026. Facts about other vendors come from their own websites, press releases, filings, Internet Archive copies and published customer work, each cited where used, most of them first checked for Bond's one-to-one comparison pages in October 2026. Bond's figures and capabilities come from its website, its technical report and product information Bond provided. We used no private or internal competitive material.

Frequently asked questions

What is EHR clinical trial matching software?
Software that reads a site's own patient records against a study's inclusion and exclusion criteria and returns the patients who may qualify, ideally with the chart evidence behind each criterion. Some tools stop at the match; Bond also contacts, pre-screens and books the matched patients.⁠[1],[2]
Which EHR trial matching software contacts patients?
Of the tools on this list, Bond is the only one whose public materials describe software that calls and texts matched patients, pre-screens them and books the visit. Tempus and Paradigm Health describe their own clinical or recruitment staff doing pre-screening or outreach, Triomics sends matches to site staff, and TriNetX sends study invitations to organizations and sites.⁠[2],[5],[19],[14],[27]
Is Deep 6 AI still available?
Deep 6 AI is part of Tempus since March 11, 2025, and deep6.ai no longer loads. Tempus sells trial matching through TIME and Next Trials.⁠[3],[12],[6] See Bond vs Tempus (Deep 6 AI).
What happened to Mendel?
Mendel's investor Oak HC/FT lists it as merged into Ensemble Health Partners, and a Forbes Councils profile says Ensemble acquired it in July 2025. We found no current Mendel product on Ensemble's website.⁠[23],[24]
How much does EHR trial matching software cost?
Of the five tools here, only Bond publishes how it charges: a volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee.⁠[2] Tempus names the trial sponsor as the TIME customer, in 2023 Paradigm Health said its customers were trial sponsors, not health systems, and TriNetX's member organizations incur no financial costs while sponsors and CROs fund the platform.⁠[3],[22],[28]

Sources

  1. 1.
    Bond Health: platform overview, FAQ and pricing · Bond Health, 2026
  2. 2.
    Bond Health product information · Bond Health, 2026Capabilities, pricing and compliance status described by Bond Health, October 2026.
  3. 3.
    Tempus AI, Inc. Form 10-K for fiscal year ended December 31, 2025 · Tempus AI, Inc. / U.S. Securities and Exchange Commission, 2026
    Filed February 2026, accessed September 2026; re-checked October 23, 2026. Quote: "On March 11, 2025, the Company acquired all of… moreFiled February 2026, accessed September 2026; re-checked October 23, 2026. Quote: "On March 11, 2025, the Company acquired all of the issued and outstanding interests of Deep 6 AI, Inc." Revenue: "The Company's Trials product includes TIME clinical trial matching services and other clinical trial services"; "To the extent the contract requires, the Company may also assist in opening the clinical trial site and enrolling the patient in the clinical trial"; "depending on the type of agreement"; "revenue is recognized upon one of the following: delivery of a notification to the physician alerting them to a clinical trial match, or once a patient is enrolled in a trial"; "the customer, which is the clinical trial sponsor". Data connections: "We use a variety of near real-time connections (e.g., HL7, FHIR) and batch data exchanges"; "Our proprietary tools connect to a provider's EHR system, data warehouse, or third-party data provider to pull out relevant structured and unstructured data that the provider has agreed to provide to Tempus"; "In certain circumstances, we cover the actual direct costs associated with the technical integrations needed to create a data connection."
  4. 4.
    Tempus Announces Acquisition of Deep 6 AI · Tempus AI, Inc. press release, 2025
    Press release dated March 11, 2025, read October 23, 2026. Quotes: "today announced it has acquired Deep 6 AI, a leading… morePress release dated March 11, 2025, read October 23, 2026. Quotes: "today announced it has acquired Deep 6 AI, a leading AI-powered precision research platform for healthcare organizations and life sciences companies" and "Its AI-powered software matches patients to clinical trials by mining real-time structured and unstructured electronic medical record (EMR) data".
  5. 5.
    Tempus TIME Clinical Trial Matching for Providers · Tempus AI, Inc. (tempus.com), 2026
    Read October 23, 2026. Quote: trial matching "with a clinical team of experts pre-screening the matched patients and presenting… moreRead October 23, 2026. Quote: trial matching "with a clinical team of experts pre-screening the matched patients and presenting potentially eligible patients with a white-glove service to each site" and, under enhanced patient pre-screening, "Generative AI scans structured and unstructured clinical notes, enhancing identification of patients who may be eligible for trial participation."
  6. 6.
    Tempus Next Trials · Tempus AI, Inc. (tempus.com), 2026
    Read October 23, 2026. Quotes: "AI-enabled platform supports clinical trial pre-screening based on your patients' multimodal,… moreRead October 23, 2026. Quotes: "AI-enabled platform supports clinical trial pre-screening based on your patients' multimodal, structured and unstructured health information (clinical, imaging and molecular data)"; "Accelerate accrual to trials already open at your practice"; "AI-enhanced workflows are designed to assist site clinicians in identifying, screening and enrolling eligible patients for TIME trials."; "When ready, Next Trials can be expanded to pre-screen patients across additional disease groups beyond oncology."
  7. 7.
    Clinical Trials for Patients | Tempus TIME · Tempus AI, Inc. (tempus.com), 2026
    Read October 23, 2026. Quote: "A Tempus Nurse Navigator will contact you within 1 business day to share information about trials… moreRead October 23, 2026. Quote: "A Tempus Nurse Navigator will contact you within 1 business day to share information about trials in our network that may be a match for you"; "Our Nurse Navigators can also speak with you and your doctor"; "The cancer clinical trials in the TIME program cover various cancer types, cancer stages, and biomarkers."
  8. 8.
    Doug Cassidy Appointed President of the Deep 6 AI Precision Research Ecosystem · Deep 6 AI (PR Newswire), 2024
    Company press release, July 24, 2024. Quote: "Healthcare organizations that become part of the Ecosystem use the company's… moreCompany press release, July 24, 2024. Quote: "Healthcare organizations that become part of the Ecosystem use the company's AI-powered software platform enterprise-wide for investigator-initiated, government-funded, and sponsored trials. Often, the technology is managed centrally (i.e., by the Clinical Trials Office)" and "the launch of our life sciences vertical in 2021".
  9. 9.
    Deep 6 AI Expands its Recruitment Acceleration Solution for Life Sciences · Deep 6 AI (PR Newswire), 2023
    Company press release, December 6, 2023. Quote: "Life sciences companies can share AI-matched patient cohorts with IRB-approved… moreCompany press release, December 6, 2023. Quote: "Life sciences companies can share AI-matched patient cohorts with IRB-approved site staff across the Deep 6 AI ecosystem. This allows sites to identify each patient, validate their eligibility with evidence in the EMR, and track their recruitment statuses" and "The site's research team can easily identify eligible patients treated by physicians other than the principal investigator, validate them, and track referrals inside the EMR."
  10. 10.
    Texas Tech University Health Sciences Center Partners with Deep 6 AI to Launch an AI Program for Clinical Trials · Deep 6 AI (PR Newswire), 2023
    Company press release, August 1, 2023. Quote: Deep 6 AI uses natural language processing to search "structured and unstructured… moreCompany press release, August 1, 2023. Quote: Deep 6 AI uses natural language processing to search "structured and unstructured EMR data points, such as physician notes, lab reports, outpatient notes, radiology reports, genomics results, and pathology reports" and "By integrating with TTUHSC's EMR, Deep 6 AI's software platform can precision-match patients to trials".
  11. 11.
    Integrating AI-Enabled Clinical Trial Matching into Operations · Stillman R, Campbell A, Humphries K, Schweitzer C. The Ohio State University Comprehensive Cancer Center; AACI CRI 2024 abstract, 2024
    Customer work-in-progress abstract on Deep 6 AI at Ohio State, accessed September 2026; re-checked October 23, 2026. Quote: "a… moreCustomer work-in-progress abstract on Deep 6 AI at Ohio State, accessed September 2026; re-checked October 23, 2026. Quote: "a user interface that speeds patient screening by presenting and highlighting patient data related to the inclusion/exclusion criteria across a longitudinal patient record"; "to be able to reference the text in which the NLP identified the keywords to view the keywords in context to confirm the finding"; "Deep 6 AI can incorporate multiple data sources beyond the electronic medical records (EMR), such as genomics, custom databases, cancer registries, CTMS, etc."
  12. 12.
    Deep 6 AI homepage (archived) · Deep 6 AI, via the Internet Archive, 2026
    Internet Archive copy of January 3, 2026. Quotes: "Deep 6 AI has joined Tempus." and "Deep 6 AI is now a Tempus AI company".… moreInternet Archive copy of January 3, 2026. Quotes: "Deep 6 AI has joined Tempus." and "Deep 6 AI is now a Tempus AI company". deep6.ai itself did not load when we checked on October 23, 2026.
  13. 13.
    Triomics homepage · Triomics, 2026
    Accessed October 2026. Quotes: "Built for cancer care's complexity"; "Our AI agents reason across every note, report and fax in a… moreAccessed October 2026. Quotes: "Built for cancer care's complexity"; "Our AI agents reason across every note, report and fax in a patient's record and deliver structured, cited answers … directly into the workflows that run a cancer center."; "Coordinators stop reading charts to rule patients out."
  14. 14.
    PRISM: clinical trial matching · Triomics, 2026
    Accessed October 2026. Quotes: "PRISM screens every upcoming patient on tomorrow's schedule and the week ahead against every… moreAccessed October 2026. Quotes: "PRISM screens every upcoming patient on tomorrow's schedule and the week ahead against every active trial in your portfolio, then refreshes the results nightly as each visit approaches."; "Matches arrive as an EHR in-basket message or in the PRISM worklist before clinic starts"; "Matches can surface as in-basket or email notifications when the chart updates"; "PRISM re-evaluates eligibility every time the chart updates"; "Federally funded, investigator-initiated, industry-sponsored. Your full portfolio, no exceptions."; "Native in Epic, Cerner, OncoEMR. Approved on the Epic App Marketplace."
  15. 15.
    Triomics for cancer centers · Triomics, 2026
    Accessed October 2026. Quotes: "HL7, FHIR, CCDAs, XMLs, PDFs, TIFFs, JPEGs."; "Native integrations with Epic, OncoEMR, iKnowMed.… moreAccessed October 2026. Quotes: "HL7, FHIR, CCDAs, XMLs, PDFs, TIFFs, JPEGs."; "Native integrations with Epic, OncoEMR, iKnowMed. Approved on the Epic App Marketplace. Outputs land in in-baskets, worklists, and EHR notes."
  16. 16.
    AI-Native Clinical Trial Platform for Sponsors and Providers · Paradigm Health, 2026
    Accessed October 2026. Quotes: "Clinical Research, Re-Engineered for Impact"; "It seamlessly combines technology and services,… moreAccessed October 2026. Quotes: "Clinical Research, Re-Engineered for Impact"; "It seamlessly combines technology and services, integrating directly with health provider organizations".
  17. 17.
    The Clinical Trial Platform Built for Care Providers · Paradigm Health, 2026
    Accessed October 2026. Quotes: "Paradigm Health removes administrative friction and coordinates directly with sponsors and CRO… moreAccessed October 2026. Quotes: "Paradigm Health removes administrative friction and coordinates directly with sponsors and CRO partners to get trials live faster."; "Match, pre-screen, and consent patients with the unprecedented speed of Paradigm Health's AI-driven Platform, backed by highly experienced clinical staff."; "Seamlessly navigate patients to trial options at their next appointment".
  18. 18.
    Paradigm Health for sponsors · Paradigm Health, 2026
    Accessed October 2026. Quotes: "Paradigm Health delivers a unified, AI-powered research model for Phase I- IV clinical trials";… moreAccessed October 2026. Quotes: "Paradigm Health delivers a unified, AI-powered research model for Phase I- IV clinical trials"; "We are the end-to-end research partner of choice for community healthcare providers and academic medical centers across the United States, Japan, and Israel."
  19. 19.
    Patient identification and trial enrollment · Paradigm Health, 2026
    Accessed October 2026. Quotes: "The platform evaluates structured and unstructured clinical data against protocol-defined… moreAccessed October 2026. Quotes: "The platform evaluates structured and unstructured clinical data against protocol-defined eligibility criteria, enabling AI-supported trial matching that surfaces potential candidates for site review."; "Embedded screening workflows and clinical recruitment support help research teams confirm eligibility, coordinate outreach, and progress patients efficiently toward enrollment."; "Integrated screening workflows and dedicated Paradigm Health recruitment coordinators work in sync with site teams on a shared platform"; "Eligibility specialists maintain structured follow-up across pre-screening, consent, and screening stages"; "support interoperability through FHIR, HL7, and data warehouse integrations".
  20. 20.
    Highlands case study · Paradigm Health, 2024
    Accessed October 2026. Quotes: "data derived from unstructured text from clinical notes and pathology reports"; "automated… moreAccessed October 2026. Quotes: "data derived from unstructured text from clinical notes and pathology reports"; "automated precision matching of eligible patients to Highlands' clinical trial portfolio".
  21. 21.
    Paradigm Health acquires Flatiron Health's clinical research business and forms strategic partnership · Paradigm Health and Flatiron Health press release, 2025
    Dated December 4, 2025, accessed October 2026. Quotes: "Paradigm Health and Flatiron Health today announced that Paradigm Health… moreDated December 4, 2025, accessed October 2026. Quotes: "Paradigm Health and Flatiron Health today announced that Paradigm Health will acquire Flatiron's Clinical Research Business."; "work to natively integrate Paradigm Health's solutions into Flatiron's OncoEMR® and deploy new capabilities".
  22. 22.
    Paradigm launches … to transform clinical trial recruitment · MedCity News (Katie Adams), 2023
    Published January 31, 2023, accessed October 2026. Quote: "Paradigm does not charge health systems for access to its technology… morePublished January 31, 2023, accessed October 2026. Quote: "Paradigm does not charge health systems for access to its technology and services, Thoelke said. Instead, the company's customers are trial sponsors".
  23. 23.
    Mendel portfolio page · Oak HC/FT, 2026Read October 23, 2026. The page describes Mendel as a "Clinical data extraction and processing platform" with the status "Merged: Ensemble Health Partners".
  24. 24.
    Pradeep Prasana Kanagaraj, VP, AI Operations & Transformation, Ensemble Health Partners · Forbes Technology Council member profile
    Undated member profile, read October 23, 2026. Its company bio reads: "Mendel.ai was acquired by Ensemble Health Partners in July… moreUndated member profile, read October 23, 2026. Its company bio reads: "Mendel.ai was acquired by Ensemble Health Partners in July 2025." We found no press release from either company.
  25. 25.
    TriNetX LIVE™ · TriNetX (trinetx.com), 2026
    Read November 8, 2026. Quotes: "Assess the feasibility of your study's eligibility criteria with real-world data on millions of… moreRead November 8, 2026. Quotes: "Assess the feasibility of your study's eligibility criteria with real-world data on millions of current patients"; "Easily target and engage with the healthcare organizations and sites best aligned to your study with site and PI-level insights and communication tools"; "NLP-extracted Facts from Clinical Notes make clinical detail queryable in TriNetX LIVE™, next to the structured EHR data for the same de-identified patients."
  26. 26.
    TriNetX LIVE™ Connect: clinical trials and research recruitment · TriNetX (trinetx.com), 2026
    Read November 8, 2026. Quotes: "TriNetX LIVE™ Connect brings sponsors, contract research organizations (CROs), and healthcare… moreRead November 8, 2026. Quotes: "TriNetX LIVE™ Connect brings sponsors, contract research organizations (CROs), and healthcare organizations (HCOs) together"; "allowing sponsors and CROs to invite HCOs to participate in their studies and HCOs to compliantly re-identify eligible patients and bring new treatment opportunities to the bedside."
  27. 27.
    TriNetX LIVE™ Premium Services · TriNetX (trinetx.com), 2026
    Read November 8, 2026. Quotes: a "Select Report with patient counts, criteria analysis, and HCO names"; "We use TriNetX LIVE™… moreRead November 8, 2026. Quotes: a "Select Report with patient counts, criteria analysis, and HCO names"; "We use TriNetX LIVE™ Connect to send your study opportunity to selected HCOs and sites under consideration, leveraging our close relationships to drive responses. We then actively follow up with sites".
  28. 28.
    A global federated real-world data and analytics platform for research · Palchuk MB, London JW, Perez-Rey D, et al. JAMIA Open 2023;6(2):ooad035 (most authors are TriNetX employees), 2023
    Read in full text on Europe PMC (PMC10182857), November 8, 2026. Quotes: the network's data covers "primarily the demographics,… moreRead in full text on Europe PMC (PMC10182857), November 8, 2026. Quotes: the network's data covers "primarily the demographics, diagnoses, procedures, medications, and laboratory results found in the HCO's electronic medical record", expanded to include oncology-specific data; HCOs "provide healthcare data as a de-identified, pseudo-anonymized, or limited data set"; data "may be acquired as discrete data elements or from natural language processing of medical notes and reports"; industry participants "can run queries against the entire network to capture aggregate patient counts at each HCO" and "cannot run queries against individual HCOs"; "Industry participants provide the financial resources to support, expand, and improve the technology platform in return for access to network data"; "HCOs incur no financial costs and receive data query, analytic, and visualization capabilities, as well as the hardware needed to execute the software"; "the data resides on hardware located within the HCO's data center. A cloud-hosted option is also available."
  29. 29.
    Implementation of a commercial federated network of electronic health record data to enable sponsor-initiated clinical trials at an academic medical center · Campion TR, Sholle ET, Abedian S, et al. (Weill Cornell Medicine). International Journal of Medical Informatics, 2024, 2024
    Abstract read on Europe PMC, November 8, 2026. Quotes: "TriNetX integrated into existing institutional workflows enabled 402… moreAbstract read on Europe PMC, November 8, 2026. Quotes: "TriNetX integrated into existing institutional workflows enabled 402 requests for sponsor-initiated clinical trials, 14 % (n = 56) of which local investigators expressed interest in conducting" over a six-year period; "measurement of impact of institutional participation in the network was challenging due to lack of a common trial identifier shared across TriNetX, sponsor, and our institution."

Related pages

Bond vs Tempus vs TriNetX

Three of these tools side by side.

Read

Bond vs TriNetX

A federated research network and a recruitment platform, compared.

Read

Bond vs Tempus (Deep 6 AI)

EHR matching, outreach, booked visits and pricing.

Read

Recruitment software compared

The wider category, vendor by vendor.

Read

Identify: LLM-based EHR screening

How Bond reads the chart and explains each match.

Read

Pricing

No integration fee: a fee per screened patient plus a share of milestones from randomization on.

Read

Security

How Bond handles PHI, BAAs and audit logging.

Read

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Up to 3×

faster enrollment

90%+

matching accuracy

48 hrs

to EHR integration