Bond Health vs TriNetX

Why is Bond better than TriNetX?

• Patients, not counts. Bond returns ranked matches from the site's own records, each with the evidence behind every criterion decision and traceability to the chart, for the coordinator to review.^⁠[11] In TriNetX, industry users see aggregate counts per organization and cannot query an individual organization.^⁠[9]
• Every match contacted. Bond's voice and SMS agents start from what Identify found in the chart, skip questions the chart already answers, and can pre-screen and book a visit in one conversation, in the patient's language.^⁠[12] TriNetX's own outreach goes to organizations and sites, not patients.^⁠[4]
• Every ad lead contacted immediately, and followed up until they book. Bond creates and runs Meta and Google ad campaigns for each study. Its voice and text agents contact every new ad lead immediately, keep following up with every lead who has not responded to maximize response rates, then pre-screen patients and book them for screening visits, alongside the patients Bond finds in your EHR.^⁠[12]
• Consent support and retention. Plain-language consent support with staff escalation, then visit reminders, transportation booking, symptom and diary collection and dropout-risk alerts after enrollment. The site and PI obtain consent.^⁠[11],[12]
• Any research site, not only network members. Bond connects to Epic, Oracle Health (Cerner), MEDITECH, athenahealth, eClinicalWorks, NextGen, Veradigm and OncoEMR, and works with CRIO, Advarra OnCore, Advarra Clinical Conductor, RealTime and Veeva SiteVault, so physician groups and FQHCs can use it too.^⁠[11],[12]
• A price that follows enrollment. A volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee. See pricing.^⁠[12]

As of October 2026, Bond is the only vendor in our comparison table whose public materials describe software that both reads EHR notes against a protocol and runs its own Meta and Google ad campaigns, then contacts patients by voice and text all the way to a booked study visit.^⁠[12]

How do Bond and TriNetX compare, capability by capability?

Years in the TriNetX column show each source's date. "Not publicly documented" means we found no public description in the materials we reviewed in November 2026, not that the capability is absent.

What is TriNetX?

TriNetX connects healthcare organizations and researchers through real-world patient data. Its TriNetX LIVE™ platform lets sponsors and CROs test a protocol's eligibility criteria against the network's data, choose organizations and sites, and invite them to studies through TriNetX LIVE™ Connect.^{⁠[1],[2],[3]} Member organizations keep their data on hardware in their own data center, or use a cloud-hosted option, and in return receive query and analytics tools at no financial cost; sponsors and CROs pay for access.^⁠[9]

TriNetX is headquartered in Cambridge, Massachusetts.^⁠[5] Carlyle was its majority investor in January 2025, when its founding CEO announced he would step down.^⁠[7] In April 2023, TriNetX announced it would acquire Clinerion from Norstella.^⁠[8]

What happens after TriNetX finds a site?

The study opportunity goes to the organization, and the organization decides whether to take it. TriNetX says Connect lets sponsors and CROs invite organizations to studies and lets the organization "compliantly re-identify eligible patients".^⁠[3] From there, someone at the site still has to find each patient in the chart, call them, pre-screen them and book the visit.

Weill Cornell Medicine published its experience: over six years, TriNetX brought it 402 requests for sponsor-initiated trials, and local investigators were interested in 14% of them. Its authors found the network's effect on activation and enrollment hard to measure, because no common trial identifier was shared across TriNetX, the sponsor and the institution.^⁠[10]

That last stretch, from an accepted study to booked screening visits, is what Bond does: Identify screens the site's records against the protocol, Engage contacts and pre-screens every match, and Book puts them on the calendar.^⁠[11],[12]

Can Bond do what TriNetX is known for?

• Protocol feasibility counts: yes, at the sites that run Bond. Bond runs feasibility from the same EHR screening, giving eligible-patient counts for a protocol backed by the chart evidence behind each match, which a coordinator can check.^⁠[12]
• Criteria that live in clinical notes: yes. Bond reads clinical notes, prescriptions and lab results, plus imaging data and pathology, radiology and molecular reports, and resolves terms through a terminology graph built from 18 biomedical vocabularies.^{⁠[11],[12],[13]}
• De-identified queries across many health systems at once: no. That is what TriNetX is built for.^⁠[2],[9] Bond works inside each site's own records, which is why the two fit together.

Can a site use TriNetX and Bond together?

Yes. A sponsor or CRO can use TriNetX to judge feasibility and pick organizations, and a site that accepts the study can use Bond to find the eligible patients in its own EHR, contact and pre-screen every one, and book them for visits.^{⁠[2],[3],[11],[12]} Bond screens each patient against every open study at the site, so a patient who screens out of one study can be matched to another.^⁠[12]

1. 1

   Accept the study

   Review the opportunity the sponsor sent and confirm your site can run it.

2. 2

   Screen your own records

   Bond screens the EHR against the protocol and returns ranked matches with the chart evidence behind each criterion.^⁠[11]

3. 3

   Contact and pre-screen

   Bond's agents call and text every match, and every lead from the Meta and Google ads Bond runs, then pre-screen them.^⁠[12]

4. 4

   Book and report

   Pre-screened patients are booked into your calendar, and the dashboard reports patients matched, contacted, pre-screened, consented and randomized to the sponsor.^⁠[11]

Before any outreach, the IRB reviews the scripts. Bond's IRB submission language template covers AI-assisted outreach, and Bond signs BAAs and is HIPAA compliant (security).^⁠[11]

How was this comparison made?

Bond wrote this page in November 2026. TriNetX facts come from public sources read on November 8, 2026: TriNetX web pages, a TriNetX press release, a Norstella press release, a peer-reviewed paper written mostly by TriNetX staff and a Weill Cornell Medicine paper, each quoted in the sources below. We left out network-size figures, which TriNetX reports differently across its own pages. Bond's figures and capabilities come from its website, its technical report and product information Bond provided. We used no private or internal competitive material.