Comparison

Bond Health vs SubjectWell (now Clariness)

SubjectWell built a patient marketplace: general online ads drew people in, SubjectWell pre-screened them by phone and referred likely candidates to research sites, charging only for patients who randomized.⁠[1],[3] In January 2026 it merged with Clariness, and the combined company operates under the Clariness name.⁠[11] Bond Health starts from the patients a site already treats, screening its EHR against each protocol, and creates and runs Meta and Google ad campaigns for each study. Its voice and text agents contact every lead immediately, follow up until they respond, pre-screen them and book the screening visit, then support consent.⁠[23],[24] For a site, CRO or sponsor that wants one platform from chart match or ad click to a booked visit, rather than referrals for staff to follow up, Bond is the stronger choice.

By Rishabh Goel, CEO · Reviewed by Steven Tan, Security LeadLast updated Nov 8, 202626 sources
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On this page

Why is Bond better than SubjectWell?

Up to 3x⁠[23]

faster enrollment than manual recruitment

3x⁠[23]

contact rate with voice and SMS/text outreach

48 hours⁠[23]

to full EHR integration, with no integration fee

  • It starts with patients your site already knows. SubjectWell's model began with people who answered general-interest ads.⁠[1] Bond's Identify screens your EHR first, reading clinical notes, prescriptions and lab results, with chart evidence for every criterion.⁠[23],[24] Published research favors that starting point: in one trial, 30.3% of provider referrals were randomized, against 4.3% of Facebook self-referrals.⁠[21]
  • Every ad lead contacted immediately, and followed up until they book. Bond creates and runs Meta and Google ad campaigns for each study. Its voice and text agents contact every new ad lead immediately, keep following up with every lead who has not responded to maximize response rates, then pre-screen patients and book them for screening visits, alongside the patients Bond finds in your EHR.⁠[24]
  • The visit is booked, not handed off. In 2023 SubjectWell connected the patient to the site, and the site continued screening and scheduled the first visit; Clariness now asks sites to process referrals within 3 to 5 working days.⁠[3],[12] Bond's agents pre-screen patients and book the screening visit in the same conversation.⁠[24]
  • Consent support in the same workflow. Bond's Consent support explains the consent form in plain language, answers patient questions and escalates to staff, while the site and PI obtain consent.⁠[23] Trial consent support is not publicly documented in SubjectWell's or Clariness's materials (November 2026).⁠[12],[5]
  • Every open study at once, from the chart. SubjectWell screened marketplace patients against several studies at once.⁠[1] Bond screens each patient in your records against every open study at your site, so a patient who screens out of one study can be matched to another.⁠[24]
  • No integration fee, and a price that moves with enrollment. Bond charges a volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward (pricing).⁠[23],[24]

How do Bond and SubjectWell compare, capability by capability?

SubjectWell entries come from SubjectWell's archived pages (2023 to 2025) and Clariness's current pages, read on November 8, 2026. "Not publicly documented" means we found no public description, not that the capability does not exist.

Bond Health and SubjectWell (now Clariness), from each company's materials
CapabilityBond HealthSubjectWell (now Clariness)
One workflow from ad click or chart match to booked visit and consentEHR screening, Meta and Google ad campaigns, voice and text outreach, pre-screening, visit booking and consent support in one platform, with a real-time dashboard and audit trail from first match to booked visit and signed consent.⁠[23],[24]Recruitment services: advertising and a patient marketplace, phone pre-screening, then referral to sites. In 2025, Patient Companions also offered warm transfers and site visit scheduling as services.⁠[3],[5]
Where patients come fromThe site's own EHR, screened against each protocol, plus Meta and Google ad campaigns Bond creates and runs for each study.⁠[23],[24]Non-study-specific online advertising feeding a patient marketplace (2023). Since the merger, Clariness's ClinLife portal, paid social, search and patient communities.⁠[1],[12],[13]
Screening the site's own patients in the EHRReads clinical notes, prescriptions and lab results, plus imaging data and pathology, radiology and molecular reports, with chart evidence for every criterion. Each patient is screened against every open study at the site (Identify).⁠[23],[24]Not publicly documented. With the patient's consent, SubjectWell retrieved full medical records to confirm eligibility (2025).⁠[5]
Pre-screeningVoice and text agents pre-screen chart matches and ad leads alike; for EHR matches they skip questions the chart already answers.⁠[24]Online questions, then telephone pre-screening against IRB-approved questionnaires (2023). Clariness describes digital smart-screening through ClinLife.⁠[3],[13]
First contact and follow-upEvery new ad lead is contacted immediately by voice and text, and the agents keep following up with every lead who has not responded. Patients are told AI is used and can reach a person at any time (Engage).⁠[24],[23]SubjectWell called each patient to confirm their online answers (2023). Clariness says it follows up and recontacts patients on behalf of sites.⁠[3],[14]
Booking the screening visitThe agents pre-screen and book the screening visit in one conversation, straight onto the site's calendar, or transfer live to a coordinator or book a callback, as the site prefers (Book).⁠[24],[23]In 2023, sites scheduled the first visit after the hand-off. By 2025, Patient Companions scheduled the site screening call, and a scheduling service synced with site calendars. Clariness asks sites to process referrals within 3 to 5 working days.⁠[3],[6],[5],[12]
Informed consentPlain-language explanations, patient Q&A in the patient's preferred language, checks of understanding on key points and staff escalation, with an auditable record. The site and PI obtain consent (Consent).⁠[23],[24]Not publicly documented (November 2026).⁠[12],[5]
Support after enrollmentThe same voice and text agents send visit reminders, book transportation, collect symptoms and diaries, run side-effect check-ins and flag participants at risk of dropping out.⁠[24]Appointment reminders from its concierge team (2023), and patient support to reduce drop-off (2025).⁠[3],[5]
Reporting for the siteA real-time dashboard and audit trail report patients matched, contacted, pre-screened, consented and randomized, plus time to enrollment and coordinator hours saved.⁠[23]A reporting portal with weekly site status updates (2023), the Performance Portal (2024) and the OneView portal, launched in February 2025.⁠[3],[4],[7]
EHR and CTMS integrationAll the major EHRs, including Epic, Oracle Health (Cerner), MEDITECH, athenahealth, eClinicalWorks, NextGen, Veradigm and OncoEMR, with full integration in 48 hours and no integration fee. Works with CRIO, Advarra OnCore, Advarra Clinical Conductor, RealTime and Veeva SiteVault, and is a CRIO Certified Partner with a two-way CRIO integration.⁠[23],[24]RealTime-CTMS integrates with SubjectWell's advertising campaigns, and SubjectWell referrals flowed into Reify Health's StudyTeam from 2021. Clariness describes API connectivity into site systems without naming a CTMS. Site EHR integration: not publicly documented.⁠[17],[18],[12]
PricingA volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee (pricing).⁠[23],[24]SubjectWell: pay only for patients who randomize (2023). Clariness: outcome-based pricing, balanced across setup and systems, outreach and media, and performance delivery. No published prices.⁠[2],[12]
Who it servesResearch sites, plus CROs that want consistent metrics across sites and sponsors that want faster enrollment timelines.⁠[23]Biopharma sponsors, CROs and study sites, under the Clariness name since January 2026.⁠[11]

What changed when SubjectWell became Clariness?

  • Ownership. WindRose Health Investors acquired SubjectWell in April 2024. SubjectWell acquired PatientCentra in November 2023 and Trials24 in September 2024.⁠[8],[9],[10]
  • The merger. On January 27, 2026, Clariness and SubjectWell announced their merger; the combined organization operates under the Clariness name. Clariness named Jim Corrigan chief executive in March 2026.⁠[11],[16]
  • The website. As of November 8, 2026, subjectwell.com redirects to the Clariness homepage, and Clariness's ClinLife portal is one of three enrollment platforms in the Clariness Hub.⁠[15],[12]
  • Pricing. Clariness's FAQ answers whether it will keep the 100% randomization commercial models SubjectWell was known for: it remains committed to outcome-based pricing, but balanced across setup and systems, outreach and media, and performance delivery.⁠[12]

If you used SubjectWell, ask Clariness which fees now apply before randomization, which site systems its API connects to, and who books the first visit. Bond's terms are on its pricing page: a volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee.⁠[24]

Can Bond do what SubjectWell is known for?

  • Paying for randomized patients. SubjectWell charged only for patients who randomized.⁠[2] Bond ties part of its price to randomization, a percentage of each randomized patient's milestone payments, alongside a volume-based fee per screened patient.⁠[23],[24]
  • Screening for several studies at once. SubjectWell screened patients against multiple studies' criteria at once.⁠[1] Bond screens each patient against every open study at your site.⁠[24]
  • Medical records behind eligibility. SubjectWell retrieved records with patient consent to confirm eligibility.⁠[5] Bond reads the record where it already lives, in your EHR, and shows the chart evidence for every criterion.⁠[23]
  • Warm transfers to sites. SubjectWell's Patient Companions offered warm transfers.⁠[5] Bond's agents transfer calls live to your coordinators or book a callback, whichever your site prefers.⁠[24]
  • RealTime integration. RealTime-CTMS integrates with SubjectWell's campaigns.⁠[17] Bond's referrals, recruitment status and outcomes move through RealTime's API or a file export; see Bond and RealTime.⁠[23]

What does a marketplace referral ask of the site?

Each referral still has to be reached, screened and booked, and when the vendor hands off, that work falls to site staff. Clariness's own 2024 data put the average time for sites to make first patient contact at 17 days, and to schedule a patient's first visit at 30.5 days.⁠[19] In a May 2026 survey of 100 US sites, 52% said at least one in five referrals is ruled ineligible before formal screening.⁠[20]

Bond moves that work to its agents. Every lead from the Meta and Google ad campaigns Bond creates for your study is contacted immediately, followed up until they respond, pre-screened and booked, and each EHR match arrives with its chart evidence.⁠[24],[23] Like any recruitment material, the ads go to your IRB first: FDA treats advertising as the start of informed consent.⁠[22]

What evidence does Bond publish?

Published figures. Bond's website reports 90%+ matching accuracy, 50%+ less chart review, a 3x contact rate and up to 3x faster enrollment than manual recruitment.⁠[23]

Technical report. Bond's matching method is written up in a technical report with results on public benchmarks, including 0.9312 micro F1 on the held-out n2c2 2018 cohort-selection task. The report is an August 2026 preprint that has not been peer reviewed, and it is available on request.⁠[26]

Security and compliance. Bond is HIPAA compliant and SOC 2 Type I compliant, its information security management system is certified to ISO/IEC 27001:2022 by Advantage Partners, and its SOC 2 Type II audit is underway.⁠[24] Its public Trust Center lists 73 HIPAA Security Rule controls, monitored continuously by Vanta.⁠[25] Bond signs BAAs; the security page has the details.⁠[23]

How can you test Bond against SubjectWell on your own data?

Each company's figures come from its own methods, so the clearest comparison is a head-to-head pilot on the same protocol, and Bond welcomes one.

  1. 1

    Pick one protocol

    Choose a study SubjectWell is already recruiting for, or one you would give it, so both work the same criteria.

  2. 2

    Screen your EHR with Bond

    Identify ranks matches with chart evidence for each criterion. Have coordinators adjudicate a sample, including borderline cases, under a BAA.

  3. 3

    Give Bond part of the same leads

    A Bond pilot can run outreach, pre-screening and scheduling on a list the site already has, such as ad leads or referrals, before EHR integration.⁠[23]

  4. 4

    Track every source to randomization

    Record leads, first contact, booked visits, screen failures and randomizations by source, with the days between each step.

  5. 5

    Compare cost per randomized patient

    Add every fee and the coordinator hours each source used, then divide by randomizations. The cost per randomized patient calculator does the arithmetic.

Bring one protocol. We will show how Bond finds patients for it in your EHR and through its own ads, and how its agents contact, pre-screen and book them.

Book a demoSee pricing

How was this comparison made?

Bond Health, which sells recruitment software and competes with SubjectWell, wrote this page in November 2026. Statements about SubjectWell come only from public sources read on November 8, 2026: Internet Archive copies of SubjectWell's website from 2023 to 2025, Clariness's current website and FAQ, press releases, and RealTime's and Reify Health's announcements. We do not repeat SubjectWell's performance or audience-size claims, and where its materials are silent on a capability we say it is not publicly documented rather than guess. Statements about Bond come from Bond's website, product information, Trust Center and technical report. SubjectWell, Clariness and ClinLife are trademarks of their owners. Bond Health is not affiliated with or endorsed by SubjectWell.

Frequently asked questions

Is Bond better than SubjectWell?
Yes. Bond finds eligible patients in your EHR, with chart evidence for every criterion, and creates and runs Meta and Google ad campaigns for your study. Its voice and text agents contact every lead immediately, follow up until they respond, pre-screen them and book the screening visit, and Bond supports informed consent, all in one platform with no integration fee.⁠[23],[24]
What happened to SubjectWell?
SubjectWell merged with Clariness in January 2026, and the combined company operates under the Clariness name.⁠[11] As of November 8, 2026, subjectwell.com redirects to the Clariness homepage.⁠[15]
Does SubjectWell still charge only for randomized patients?
Clariness says it remains committed to outcome-based pricing, but with models balanced across setup and systems, outreach and media, and performance delivery, rather than the 100% randomization model SubjectWell was known for.⁠[12] Bond charges a volume-based fee per screened patient plus a percentage of each randomized patient's milestone payments, from randomization onward, with no integration fee.⁠[23],[24]
Can Bond follow up leads we already have from SubjectWell or Clariness?
Yes. A Bond pilot can run outreach, pre-screening and scheduling on a list the site already has, such as ad leads or referrals, before the EHR is connected. Patients are told AI is used and can reach a person at any time.⁠[23]

Sources

  1. 1.
    SubjectWell: Risk-Free Recruitment (homepage, archived) · SubjectWell, via the Internet Archive, 2023
    Captured January 17, 2023; read November 8, 2026. Quotes: "Pay only for patients who randomize"; "Our non-study-specific online… moreCaptured January 17, 2023; read November 8, 2026. Quotes: "Pay only for patients who randomize"; "Our non-study-specific online advertising is running on tens of thousands of general interest websites"; "following up with telephone-based prescreening"; "we contact these patients to screen them against criteria for multiple studies at once".
  2. 2.
    SubjectWell pricing (archived) · SubjectWell, via the Internet Archive, 2023Captured February 7, 2023; read November 8, 2026. Quote: "if we don't randomize a patient into your trial, you pay absolutely nothing".
  3. 3.
    SubjectWell: Our Approach (archived) · SubjectWell, via the Internet Archive, 2023
    Captured February 7, 2023; read November 8, 2026. Quotes: "we call the patient, confirm the information already provided online,… moreCaptured February 7, 2023; read November 8, 2026. Quotes: "we call the patient, confirm the information already provided online, and proceed to screen them" ... "using IRB-approved questionnaires"; "sites continue the screening discussion and schedule the patient's first visit"; "we ask the site to provide a weekly update on the patient's status"; "our concierge team stays in touch with them, providing additional support and appointment reminders".
  4. 4.
    SubjectWell: The Patient Access Marketplace (homepage, archived) · SubjectWell, via the Internet Archive, 2024Captured July 8, 2024; read November 8, 2026. Quote: "a unique Performance Portal™ for tracking progress, all supported by our private contact center".
  5. 5.
    SubjectWell: Services (archived) · SubjectWell, via the Internet Archive, 2025
    Captured February 8, 2025; read November 8, 2026. Quotes: "allows for warm transfers to sites"; "Our Site Visit Scheduling service… moreCaptured February 8, 2025; read November 8, 2026. Quotes: "allows for warm transfers to sites"; "Our Site Visit Scheduling service streamlines patient appointments by syncing directly with site calendars"; "With patient consent, SubjectWell retrieves full medical records to confirm eligibility"; "we minimize dropoff rates and support adherence." No description of trial informed consent support.
  6. 6.
    Rethink patient recruitment with SubjectWell (homepage, archived) · SubjectWell, via the Internet Archive, 2025Captured July 10, 2025; read November 8, 2026. Quote: "SubjectWell's Patient Companions schedule the site screening call for patients."
  7. 7.
    SubjectWell Launches OneView Portal to Transform and Streamline Patient Recruitment (archived) · SubjectWell, via the Internet Archive, 2025Press release dated February 4, 2025; read November 8, 2026. Quote: "today announced the launch of its OneView recruitment portal and company rebrand".
  8. 8.
    WindRose Health Investors Completes Majority Growth Investment in SubjectWell (archived) · SubjectWell, via the Internet Archive, 2024News post dated April 30, 2024; read November 8, 2026. Quote: "announced that it has completed the acquisition of SubjectWell, the patient access marketplace".
  9. 9.
    SubjectWell Acquires PatientCentra (archived) · SubjectWell, via the Internet Archive, 2023Dated November 2, 2023; read November 8, 2026. Quote: "announced the acquisition of PatientCentra".
  10. 10.
    SubjectWell Announces Strategic Acquisition of Trials24 to Expand Global Patient Recruitment Capabilities (archived) · SubjectWell, via the Internet Archive, 2024Dated September 2024 (September 17 in SubjectWell's news list); read November 8, 2026.
  11. 11.
    Clariness and SubjectWell Merge to Form Global, Full-Service Patient Recruitment Platform · Clariness and SubjectWell (PR Newswire), 2026
    Press release dated January 27, 2026; read November 8, 2026. Quotes: "Clariness and SubjectWell announced their merger"; WindRose,… morePress release dated January 27, 2026; read November 8, 2026. Quotes: "Clariness and SubjectWell announced their merger"; WindRose, "which previously acquired SubjectWell in April 2024"; "The combined organization will operate under the Clariness name." Customers are described as "biopharma sponsors, CROs, and study sites across the globe".
  12. 12.
    FAQs · Clariness, 2026
    Read November 8, 2026. Question: "Will you continue to offer 100% randomization commercial models that SubjectWell is known for?"… moreRead November 8, 2026. Question: "Will you continue to offer 100% randomization commercial models that SubjectWell is known for?" Answer: "We are fully committed to outcome-based pricing", with models "more balanced across three key areas: setup and systems, outreach and media, and performance delivery". Also: "ClinLife is now one of three enrollment platforms that make the Clariness Hub"; channels include "paid social including Meta and other platforms, search, display, patient communities"; "We request that sites process referrals within 3-5 working days"; "API connectivity into existing site systems". No description of trial informed consent support.
  13. 13.
    ClinLife® powers patient recruitment · Clariness, 2026
    Read November 8, 2026. Quotes: "Digital smart-screening of patients, assessing eligibility and site fit"; patients "are scheduled… moreRead November 8, 2026. Quotes: "Digital smart-screening of patients, assessing eligibility and site fit"; patients "are scheduled or live transferred to their preferred site".
  14. 14.
    Giving sites the support they need to accelerate enrollment · Clariness, 2026Read November 8, 2026. Quote: "Follow-up and recontact patients on behalf of sites".
  15. 15.
    Clariness homepage · Clariness, 2026
    Read November 8, 2026. Quote: "Following our merger with SubjectWell, we've combined our capabilities, technologies, global… moreRead November 8, 2026. Quote: "Following our merger with SubjectWell, we've combined our capabilities, technologies, global infrastructure". On November 8, 2026, https://subjectwell.com/ returned a 301 redirect to this page.
  16. 16.
    Clariness announces Jim Corrigan as CEO to lead next phase of growth · Clariness, 2026Dated March 31, 2026; read November 8, 2026. Quote: "announced Jim Corrigan as Chief Executive Officer".
  17. 17.
    CTMS Integrations · RealTime eClinical Solutions (blog), 2022Dated June 28, 2022; read November 8, 2026. Quote: "RealTime-CTMS integrates with SubjectWell's study-specific advertising campaigns."
  18. 18.
    Reify Health and SubjectWell Launch Partnership to Boost Patient Recruitment for Clinical Trials · Business Wire release, reposted by Frontier Venture Capital, 2021
    Original release dated March 31, 2021; read November 8, 2026. Quote: "referrals from SubjectWell's marketplace are delivered… moreOriginal release dated March 31, 2021; read November 8, 2026. Quote: "referrals from SubjectWell's marketplace are delivered directly into Reify Health's StudyTeam™".
  19. 19.
    The 3 KPIs to follow for clinical trial site success · Clariness, 2024
    Vendor blog dated May 29, 2024, based on Clariness's global site experience. Quotes: "Our data shows that on average, it takes… moreVendor blog dated May 29, 2024, based on Clariness's global site experience. Quotes: "Our data shows that on average, it takes sites 17 days to make first patient contact." and "sites take an average of 30.5 days to schedule the first visit of a patient."
  20. 20.
    The Referral Readiness Gap: What 100 U.S. Clinical Trial Sites Told Us About Referral Quality · myTomorrows, 2026
    Vendor-sponsored survey of 100 US site professionals, fielded May 2026, published July 14, 2026; the post does not break referrals… moreVendor-sponsored survey of 100 US site professionals, fielded May 2026, published July 14, 2026; the post does not break referrals down by source. Quote: "In our survey, 52% of sites said at least one in five referrals are ruled ineligible before formal screening even begins".
  21. 21.
    Recruiting for a Randomized Clinical Trial for Late-Life Depression During COVID-19: Outcomes of Provider Referrals Versus Facebook Self-Referrals · Ainsworth NJ, et al. American Journal of Geriatric Psychiatry 2023;31(5):366-371, 2023Quote: "Provider referrals had a significantly higher yield (10 of 33 referrals; 30.3%) versus Facebook self-referrals (14 of 323; 4.3%) (p <0.00001)."
  22. 22.
    Recruiting Study Subjects: Guidance for Institutional Review Boards and Clinical Investigators · U.S. Food and Drug Administration, 1998
    Guidance dated January 1998. Quote: "FDA considers direct advertising for study subjects to be the start of the informed consent… moreGuidance dated January 1998. Quote: "FDA considers direct advertising for study subjects to be the start of the informed consent and subject selection process. Advertisements should be reviewed and approved by the IRB as part of the package for initial review."
  23. 23.
    Bond Health: platform overview, FAQ and pricing · Bond Health, 2026
  24. 24.
    Bond Health product information · Bond Health, 2026Capabilities, pricing and compliance status described by Bond Health, October 2026.
  25. 25.
    Bond Health Trust Center · Bond Health, monitored by Vanta, 2026
    Lists 73 HIPAA Security Rule controls: infrastructure security (20), organizational security (14), internal security procedures… moreLists 73 HIPAA Security Rule controls: infrastructure security (20), organizational security (14), internal security procedures (38), and data and privacy (1), monitored continuously by Vanta.
  26. 26.
    Terminology Infrastructure and Graph-Grounded RAG for Clinical Trial Patient Matching · Bond Health, preprint, 2026Internal technical report by R. Goel, August 2026. Not peer reviewed. Available on request.

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